The film concerns the intertwining stories of three groups of people who meet due to a traffic accident on a section of Taiwan's Suhua Highway—an unforeseen blow that serves as a turning point in all of their lives. Everyone in Taiwan, from the middle classes down to the homeless, must constantly be on the move in order to get by which creates spiritual instability. God Man Dog presents an image of constant movement that starts externally and gradually infects the soul, and reminds us that we all are lost yet continue to struggle.